| Product Name | Polyphyllin I |
|---|---|
| CAS | 50773-41-6 |
| Formula | C44H70O16 |
| MW | 855.021 |
| Appearance | 白色粉末 |
| PKa | 12+-.0.70 | Condition: Most Acidic Temp: 25 °C |
| Product Name | Polyphyllin I |
|---|---|
| CAS | 50773-41-6 |
| Formula | C44H70O16 |
| MW | 855.021 |
| Appearance | 白色粉末 |
| PKa | 12+-.0.70 | Condition: Most Acidic Temp: 25 °C |
WKQ-0000727
中文名称：重楼皂苷I
中文别名：重楼皂甙I；重楼皂苷Ⅰ；重楼皂甙A；重楼皂甙
英文名称：Polyphyllin I
英文别名：(3β,25R)-Spirost-5-en-3-yl O-α-L-arabinofuranosyl-(1→4)-O-[6-deoxy-α-L-mannopyranosyl-(1→2)]-β-D-glucopyranoside;Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran], β-D-glucopyranoside deriv.;Spirostan, β-D-glucopyranoside deriv.;(+)-Polyphyllin D;17-Deoxyparis H;Diosgenin 3-O-α-L-arabinofuranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside;Diosgenin 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-arabinofuranosyl-(1→4)]-β-D-glucopyranoside;Diosgenin 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-arabinofuranosyl-(1→4)]-β-D-glucopyranoside;Diosgenin 3-O-α-L-rhamnopyranosyl-(1→4)-[α-L-arabinopyranosyl-(1→2)]-β-D-glucopyranoside;Diosgenin-3-α-L-arabinofuranosyl(1→4)-[α-L-rhamnopyranosyl(1→2)]-β-D-glycopyranoside;Paridis saponin I;Paris I;Paris saponin I;Paris saponin Pa;Polyphillin D;Polyphyllin D;Polyphyllin I;Saponin Pa;
分子式：C44H70O16
分子量：855.02
CAS号：50773-41-6
纯度：HPLC≥98%
密度：1.40±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
酸系度数：12+-.0.70 | Condition: Most Acidic Temp: 25 °C
储存条件：-20℃，干燥、避光、密封
规格：5mg10mg20mg50mg100mg500mg1g2g等应客户需求包装
供应单位：四川省维克奇生物科技有限公司
供应电话：028-81700200/4008005713
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| Efficient enzyme-catalyzed production of diosgenin: inspired by the biotransformation mechanisms of steroid saponins in Talaromyces stollii CLY-6 | ||
| Source:SCI：GREEN CHEMISTRY | Author:Leiyu Cheng | Notes：影响因子：10.182 |
| Reference description | ||
Dried tubers of Dioscorea zingiberensis C.H. Wright (DZW, Fig. 1b; powder form, P-DZW, Fig. 1c) and crude extract of DZW (E-DZW, Fig. 1d) were supplied by Zunyi City Bei Yuan Chemical Co., Ltd (China). The standard materials of diosgenin, zingiberensis newsaponin (S1), deltonin (S2), prosapogenin A (S3), trillin (S6), polyphyllin I, and dioscin were purchased from Sichuan Weikeqi Biotechnology Co., Ltd (China). Diosgenin triglucoside (S4) and diosgenin diglucoside (S5) were purified from E-DZW. All other chemicals and reagents were of analytical grade and purchased from Beijing Chemical Co., Ltd (China). | ||
| Drug interaction study of natural steroids from herbs specifically toward human UDP-glucuronosyltransferase (UGT) 1A4 and their quantitative structure activity relationship (QSAR) analysis for prediction | ||
| Source:SCI：PHARMACOLOGICAL RESEARCH | Author:Min Xu | Notes：影响因子：4.816 |
| Reference description | ||
hecogenin (1), diosgenin (2), ruscogenin (3), gitogenin (4), tigogenin (5), solasodine (6), (24S,25S)-3β, 24-di-hydroxy-5α-spirostan (7), dracaenol C (8), 25(27)-dehydroruscogenin (9), (1β, 3β, 14α, 15α, 20R, 22S, 25R)-spirost-5-ene-tetrol (10), peimine (11), peiminine (12), peimisine (13), isoverticine (14), trillin (15), polyphyllin VI (16), polyphyllin VII (17), pallidifloside D (18), prosapogenin A (19), spongipregnoloside A (20), dioscin(21), solasonine (22), solamargine (23), gracillin (24), polyphyllin I(25), timosaponin BII (26), timosaponinA-III(27), ophiopogonin D (28), protobioside (29), (22S,25S)-26-O-β-d-glucopyranosyl-22,25-epoxyfurost-5-en-3β,26-diol-3-O-α-l-rha-mnopyranosyl(1 → 2)-β-d-gluc (30), pallidifloside E (31), parispseudoside (32), methylprotodioscin (33), protodioscin (34), pseudoprotodioscin (35), YS-IX (36), pallidifloside A (37), pallidifloside H (38), digoxin (39), bisdigoxigenin (40), 7β, 14α, 21-tri-hydroxy-diosgenin (41), 12β,14α,21-tri-hydroxy-diosgenin (42), and 11β,14α-di-hydroxyldiosgenin (43) were purchase from Sichuan weikeqi biotechnology company (Sichuan province, China). Pooled human liver microsomes (HLMs, 20 mg/mL) and pooled human primary hepatocytes were purchased from Rild Research Institute for LiverDiseases (Shanghai, China). | ||
| The protective effect of polyphyllin I on myocardial ischemia/reperfusion injury in rats | ||
| Source:SCI：Annals of Translational Medicine | Author:Ruizhen Huang | Notes：影响因子：3.932 |
| Reference description | ||
PPI powder (molecular formula: C44H70O16, molecular weight: 855.017, density: 1.4±0.1 g/cm3, purity ≥98%) was obtained from Sichuan Weikeqi Biological Technology Co., Ltd. (Chengdu, China). Male Sprague-Dawley (SD) rats (≥6 weeks old, 251–300 g) were bought from Zhejiang Chinese medical university Laboratory Animal Research Center (Zhejiang, China). | ||
| Polyphyllin I combined with doxorubicin shows chemosensitization effect in vivo and reduces immunotoxicity of doxorubicin | ||
| Source:SCI：Molecular & Cellular Toxicology | Author:Zhu, Xiang | Notes：影响因子：1.08 |
| Reference description | ||
The MTT assay measured cell proliferation. MCF-7 cells, H22 cells, and S180 cells (8000 cells/well) were first seeded into 96-well plates. PPI (Weikeqi-biotech, wkq19051309) was dissolved in 100% DMSO to 100 mmol/L as a storing solution and was then diluted in normal saline (NS) to 1–1000 µmol/L as working solutions. 0.1–100 µmol/L PPI was incubated with the cells for 48 h. | ||
