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麦冬皂苷D

Ophiopogonin D

产品编号:WKQ-0753788 CAS No.:945619-74-9 纯度:HPLC≥98% 分子式:C44H70O16
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2mg 2毫克 5毫克 10毫克 20毫克 50毫克 100毫克 200毫克
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  • 相关文献
基本信息
英文名称 Ophiopogonin D
中文名称麦冬皂苷D
CAS号945619-74-9
分子式C44H70O16
分子量855.02
熔点263-265 °C
沸点-
酸度系数pKa13.01±0.70 | Condition: Most Acidic Temp: 25 °C
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相关文献
Ophiopogonin D, a Steroidal Glycoside Abrogates STAT3 Signaling Cascade and Exhibits Anti-Cancer Activity by Causing GSH/GSSG Imbalance in Lung Carcinoma
来源:SCI:Cancers 作者:Jong Hyun Lee 备注:影响因子:5.326
引用描述

Ophiopogonin D (OP-D, Figure 1A) was purchased from Sichuan Weikeqi Biological Technology Co. Ltd. (Chengdu, China). Stock solution of OP-D (100 mM) was prepared using dimethyl sulfoxide, stored at −80 °C, and diluted in cell culture medium for use. LightShift® Chemiluminescent EMSA kit

Drug interaction study of natural steroids from herbs specifically toward human UDP-glucuronosyltransferase (UGT) 1A4 and their quantitative structure activity relationship (QSAR) analysis for prediction
来源:SCI:PHARMACOLOGICAL RESEARCH 作者:Min Xu 备注:影响因子:4.816
引用描述

hecogenin (1), diosgenin (2), ruscogenin (3), gitogenin (4), tigogenin (5), solasodine (6), (24S,25S)-3β, 24-di-hydroxy-5α-spirostan (7), dracaenol C (8), 25(27)-dehydroruscogenin (9), (1β, 3β, 14α, 15α, 20R, 22S, 25R)-spirost-5-ene-tetrol (10), peimine (11), peiminine (12), peimisine (13), isoverticine (14), trillin (15), polyphyllin VI (16), polyphyllin VII (17), pallidifloside D (18), prosapogenin A (19), spongipregnoloside A (20), dioscin(21), solasonine (22), solamargine (23), gracillin (24), polyphyllin I(25), timosaponin BII (26), timosaponinA-III(27), ophiopogonin D (28), protobioside (29), (22S,25S)-26-O-β-d-glucopyranosyl-22,25-epoxyfurost-5-en-3β,26-diol-3-O-α-l-rha-mnopyranosyl(1 → 2)-β-d-gluc (30), pallidifloside E (31), parispseudoside (32), methylprotodioscin (33), protodioscin (34), pseudoprotodioscin (35), YS-IX (36), pallidifloside A (37), pallidifloside H (38), digoxin (39), bisdigoxigenin (40), 7β, 14α, 21-tri-hydroxy-diosgenin (41), 12β,14α,21-tri-hydroxy-diosgenin (42), and 11β,14α-di-hydroxyldiosgenin (43) were purchase from Sichuan weikeqi biotechnology company (Sichuan province, China). Pooled human liver microsomes (HLMs, 20 mg/mL) and pooled human primary hepatocytes were purchased from Rild Research Institute for LiverDiseases (Shanghai, China).

Ophiopogonin D modulates multiple oncogenic signaling pathways, leading to suppression of proliferation and chemosensitization of human lung cancer cells
来源:SCI:PHYTOMEDICINE 作者:Jong Hyun Lee 备注:影响因子:3.61
引用描述

Ophiopogonin D (OP-D, Fig. 1A) was purchased from Sichuan Weikeqi Biological Technology Co., Ltd (Sichuan, China). Dimethyl sulfoxide was used to prepare an OP-D stock solution (100 mM), which was then kept at −80 °C and diluted in a cell culture medium. Antibodies against IκB-α, p-IκB-α, p65, p-p65(ser276), AKT, c-Fos, c-Jun, Bcl-xL, IAP2, MMP-9, Caspase-3, PARP, Survivin, β-actin, and Lamin B, goat anti-mouse IgG-HRP

The Inhibition of the Components from Shengmai Injection towards UDP-Glucuronosyltransferase
来源:SCI:Evidence-based Complementary and Alternative Medicine 作者:Jiang Li-Peng 备注:影响因子:2.175
引用描述

UGT1A10, UGT2B4, UGT2B7, and UGT2B15) expressed in baculovirus-infected insect cells were obtained from BD Gentest Corp. (Woburn, MA, USA). Ophiopogonin D (OD), ophiopogonin D′ (OD′), methylophiopogonanone A (MA), methylophiopogonanone B (MB), and ruscorectal (RU) were purchased from Sichuan Weikeqi Biotechnology Company (Chengdu, Sichuan, China). The purity of these compounds was above 95%. All other reagents were of HPLC grade or of the highest grade commercially available.

Ophiopogonin D of <i>Ophiopogon japonicus</i> ameliorates renal function by suppressing oxidative stress and inflammatory response in streptozotocin-induced diabetic nephropathy rats
来源:SCI:BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH 作者:Qiao Yanhong 备注:影响因子:2.023
引用描述

OP-D (purity ≥98%, HLPC) was obtained from Sichuan Weikeqi Biological Techology Co. (China). STZ was obtained from Sigma-Aldrich (USA) and gliclazide (Glic, 99.2%) was obtained from the Servier (Tianjin) Pharmaceutical Co. (China).

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